Tremont AI
ToxScribe · Foundation model

A vision-language model for toxicologic pathology.

Trained across tox species and magnifications. Show it a region or a whole slide and it describes the finding, where it is and how severe.

Get access → See the encoder · TRACE
ToxScribe read Liver · H&E
H&E rat liver, 20x, bile duct hyperplasia and hepatocellular hypertrophy
200 µm
+−
TToxScribe read
ToxScribe caption

The portal area contains an increased number of variably sized bile duct profiles, lined by a single layer of cuboidal epithelium. Low numbers of lymphocytes and eosinophils infiltrate the portal area (considered within normal limits).

ToxScribe across a dose ladder

One model reads the whole dose range.

Four liver fields from a carbon tetrachloride study, one per dose group. ToxScribe calls the control normal, picks up the first vacuoles at 100 mg/kg and grades the change as it becomes marked at 300.

Control liver, H&E: uniform parenchyma with preserved lobular architecture
Control
Uniform parenchyma with preserved lobular architecture.
30 mg/kg liver, H&E: minimal centrilobular hepatocellular hypertrophy
30 mg/kg
Minimal centrilobular hepatocellular hypertrophy, adaptive and non-adverse.
100 mg/kg liver, H&E: hepatic steatosis, Grade 3
100 mg/kg
Numerous clear, round cytoplasmic vacuoles within hepatocytes, hepatic steatosis, Grade 3.
300 mg/kg liver, H&E: marked diffuse steatosis, Grade 4
300 mg/kg
Numerous clear vacuoles, marked diffuse steatosis with lipid accumulation, Grade 4.
Foundation model access

Put ToxScribe to work on your studies.

Available through Tremont Studio and to select research partners.

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